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394,395 Other signalings can interact with Hippo pathway to promote HCC, such as Notch pathway, EGFR signals, AKT pathway and DDR1 signaling 396,397,398,399 Considering the oncogenic roles of YAP in liver cancer and other disease, it is attractive to develop inhibitors targeting YAP

doi: 10.1177/17562848211048133

The studies reveal that the iminium form of CHE has a high binding affinity to DNA, but the neutral alkanolamine form does not bind to DNA

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10.1038/s41467-021-20904-2 [DOI] [PMC free article] [PubMed] [Google Scholar] Liu L., He J., Sun G., Huang N., Bian Z., Xu C., et al